* CDT: Catheter-directed thrombolysis; EKOS®: EkoSonic endovascular system; FH: Fractionated heparin (i.e., enoxaparin); LV: Left ventricle; MPE: Massive pulmonary embolism; N: No. of patients; PE: Pulmonary embolism; RV: Right ventricle; SMPE: Submassive pulmonary embolism; tPA: tissue plasminogen activator; UFH: Unfractionated heparin; USCDT: Ultrasound facilitated catheter-directed thrombolysis. The gene discussed is PLAT; the disease is pulmonary embolism.