STAT3 and colorectal cancer: We found that metastasis associated pathway and stemness related pathway were significantly enriched in miR-204-5p target genes, such as EMT pathway, colorectal cancer metastasis signaling, TGFβ signaling, mouse embryonic stem cell pluripotency, human embryonic stem cell pluripotency, STAT3 pathway and IL-6 signaling (Figure 4B), which was consistent with the IPA analysis by using the whole DEGs.