However, miRNAs are well-known to regulate multiple target genes at post-transcription level and some miR-204-5p target genes have been identified in HNSCC, including IGFBP5 40, CXCR4 41, FOXC1 42, SNAI2 and SOX4 43. The gene discussed is SNAI2; the disease is head and neck squamous cell carcinoma.