To confirm that the kinase activity of PDGFRβ was inhibited in vivo, we analyzed LLC tumor lysates from mice treated with vehicle, 1-NaPP1 or imatinib, by immunoblotting using an antibody against pTyr857; the PDGF-BB-induced phosphorylation of PDGFRβ was suppressed in mice treated with either 1-NaPP1 or imatinib (Figure 2E). The gene discussed is PDGFRB; the disease is neoplasm.