IGF1R and cancer: EGCG downregulated the expression of several anti-apoptotic genes (insulin-like growth factor-1 receptor: IGF1R; induced myeloid leukemia cell differentiation protein: MCL1) while increased the expression of other genes (B-cell lymphoma 2: Bcl2; associated athanogene 3: BAG3; receptor-interacting serine/threonine-protein kinase 2: RIPK2; X-Linked Inhibitor of Apoptosis: XIAP) probably due to resistance to cancer treatment [23].