EGFR and breast cancer: Specifically, it has been showed that EGCG inhibited breast cancer cell growth by enhancing the chemotherapeutic-induced cellular apoptosis [16], and by modulating different molecular signaling pathways as the nuclear factor-κB (NF- κβ), the epidermal growth factor receptor (EGFR), the mitogen-activated protein kinase (MAPK) and the phosphatidylinositol-3 (PI3) kinase [17–20].