MEG3 and neoplasm: As well, after 44 days, all nude mice were sacrificed for tumor weight examination and the results revealed that the tumor weight in B16-lncRNA MEG3-siRNAgroup was greater than that in B16group, whereas the tumor weight was sharply decreased in A2058-lncRNA MEG3 or A375-lncRNA MEG3 group as compared to their corresponding control groups (Fig. 3b).