We therefore determined the expression of MMP-2 and MMP-9 using western blot analysis, which showed that the protein expression of MMP-2 and MMP-9 was remarkably down-regulated in LNCaP cells upon oe-LINC00908 treatment (p < 0.05, Fig. 2b), suggesting that LINC00908 could impede the invasion and migration of PCa cells. The gene discussed is MMP2; the disease is posterior cortical atrophy.