PKD1 and Renal cyst: The tissue samples were classified into 7 distinct groups: (1) CY, including the cystic kidney samples, n = 10; (2) NC, non-cystic kidney samples, n = 10; (3) HT, Pkd1-haploinsuficient kidney samples, n = 6; (4) WT, wild-type kidney samples, n = 6; (5) SC, severely cystic kidney samples, n = 7; (6) CO, early-life, wild-type kidney samples, n = 5; and (7) All, including all kidney samples, n = 44.