Two downstream markers of STING activation, namely activating phosphorylations of STAT1 (pTyr701-STAT1) and of NF-κB (pSer536-p65) were induced in breast cancer cell lines treated with the antimitotic agent paclitaxel in vitro (Fig. 1a and Supplementary Fig. 1a). This evidence concerns the gene RELA and breast carcinoma.