Ectopic expression of FOXD3 stimulated the expression of miR-548d-3p (Supplementary Fig. 4O) and repressed JUND and RPS6KA2 mRNA expression (Supplementary Fig. 4P), as well as greatly enhancing the BET sensitivity of luminal breast cancer cells (Supplementary Fig. 4Q). Here, FOXD3 is linked to breast carcinoma.