Twenty-six types of LGMDR have been identified so far in which LGMDR1 calpain3-related (LGMD2A, calpainopathy), LGMDR2 dysferlin-related (LGMD2B, dysferlinopathy1), and sarcoglycanopathies including LGMDR5 γ-sarcoglycan-related (LGMD2C), LGMDR3 α-sarcoglycan-related (LGMD2D), LGMDR4 β-sarcoglycan-related (LGMD2E), and LGMDR6 δ-sarcoglycan-related (LGMD2F), are the most common kinds of LGMDRs and are caused by mutations in CAPN3, DYSF, SGCG (γ-sarcoglycan), SGCA (α-sarcoglycan), SGCB (β-sarcoglycan), and SGCD (δ-sarcoglycan) genes respectively [4]. The gene discussed is DYSF; the disease is sarcoglycanopathy.