In another study conducted by Fanin et al, LGMDR1 calpain-3 related was the most prevalent form in Italian patients, and sarcoglycanopathies were the second most common type, in which alpha sarcoglycanopathies were the most frequent forms [20]. The gene discussed is CAPN3; the disease is autosomal recessive limb-girdle muscular dystrophy type 2D.