Crabbe T et al. [30] and F Q Wang [31] indicated that gelatinases (e.g., MMP2 and MMP9) could be activated by MMP7, and Imai K et al. [32] demonstrated that MMP7 could enhance MMP1 activity and partially activate pro-MMP9 in human rectal carcinoma cells. This evidence concerns the gene MMP7 and rectal carcinoma.