The results showed that CIG (IG: 75, 150, 300 mg/kg) could significantly improve the glucose tolerance of diabetic mice, and CIG could enhance the expression of PI3K-Akt/PKB pathway-related proteins in insulin metabolism, through which the hyperglycemia and hyperlipidemia of diabetic mice induced by HFD and STZ could be improved [76]. The gene discussed is AKT1; the disease is hyperlipidemia.