Balakrishnan and co-workers reported the use of chemically synthesized gold nanoparticle conjugated with naturally available photochemical quercetin for the inhibition of tumor angiogenesis, epithelial–mesenchymal transition, and tumor metastasis via EGFR/VEGFR-2-controlled pathway in in vitro and in vivo breast cancer (Figure 6) [118]. This evidence concerns the gene KDR and neoplasm.