The colon cancer cell line Huh-7 and pancreatic cancer cell lines express HNF-1 [64,65,66], although they do not express B3GALT5-LTR, which may be a consequence of no or minimal methylation on the aforementioned CpG islands at site 2 upstream of the B3GALT5-LTR exon [64]. This evidence concerns the gene HNF1A and colonic neoplasm.