Interestingly, two subgroups of patients showed a statistically significant OS advantage with ICIs: PD-L1 tumour-positive patients when compared to PD-L1 tumour-negative patients (HR: 0.82 vs. 1.04 respectively, Figure 2), and patients with gastro-oesophageal junction tumours when compared to gastric tumours (HR: 0.67 vs. 0.92 respectively, Figure 3). Here, CD274 is linked to neoplasm.