While the response for M1 and M2 mRNA expression markers displayed a high data dispersion, which was reflected in high standard errors when averaging independent experiments (Figure S1a,b in Supplementary Material), we observed a significant BCC-induced upregulation of both IL6 and IL1Ra proteins, that mirrored phenotypic changes associated with M1 and M2 macrophage polarization (Figure 2d,e). This evidence concerns the gene IL6 and skin basal cell carcinoma.