PPARG and neoplasm: In addition, EPA and DHA show direct affinity for peroxisome proliferator-activated receptor gamma (PPARγ) [14], which is well-known for its metabolic functions [15], but also for its involvement in inflammation [16,17]; and in tumor suppressor action by the virtue of promoting growth inhibition, apoptosis, cell cycle arrest and re-differentiation in several malignancies [18,19,20,21].