In various cancers, curcumin has been shown to inhibit growth and proliferation of cancer cells by targeting various survival pathways, including JAK/STAT3, PI3-kinase/AKT, Transforming growth factor beta (TGF-β), Epidermal Growth Factor Receptor (EFGR), and NF-кB [17,18,19,20,21]. The gene discussed is AKT1; the disease is cancer.