PPIG and neoplasm: At day 27, the tumor size was 320.96 ± 62.09 mm3 (p < 0.0001) and 397.51 ± 90.23 mm3 (p < 0.005) for the CYP-loaded CA NPs and CYP-loaded CMCA NPs, respectively, which was almost two times less than the group treated with only CYP and six times less than the untreated group.