PPARA and hereditary clear cell renal cell carcinoma: In the MC-50 vs. MC-200 group, the target gene enrichment pathways included protein processing in the endoplasmic reticulum, RNA transport, spliceosomes, transcriptional misregulation in cancer, the PPAR signaling pathway, the mRNA surveillance pathway, pyruvate metabolism, the Wnt signaling pathway, the ErbB signaling pathway, and renal cell carcinoma (Figure 2C).