These include specific inhibitors of monocarboxylate transporter 1, hexokinase II, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), pyruvate dehydrogenase, pyruvate dehydrogenase kinase 1, cancer-specific mutant isocitrate dehydrogenase, lactate dehydrogenase A, phosphoglycerate mutase 1, phosphofructokinase, or pyruvate kinase M2 [48,50]. The gene discussed is GAPDH; the disease is cancer.