In breast cancer, ETV6-NTRK3 is expressed in 12 (92%) of 13 patients with human secretory breast carcinoma (SBC), a rare subtype of IDC, and the resulting ETV6-NTRK3 protein functions as a chimeric protein with potent transforming activity in fibroblasts [80]. This evidence concerns the gene NTRK3 and breast carcinoma.