In patients with end-stage renal failure on dialysis, the ratio of phosphorylated MYPT-1 to MYPT-1 in PBMC increased in dialysis patients with AF (DPAFs) compared to patients on dialysis without AF (DPs) as well as versus healthy controls (C): 1.57 ± 0.17 vs. 0.69 ± 0.04 vs. 0.51 ± 0.05 respectively, ANOVA: p < 0.0001. The gene discussed is PPP1R12A; the disease is atrial fibrillation.