IL4 and Alzheimer disease: Fish oil contains omega-3 polyunsaturated fatty acids (n-3 PUFAs), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and can reduce sensitization to allergens; alleviate the severity of AD, eczema, and asthma; and inhibit the expression of IL-1, IL-4, and IL-13 in serum [8,9,10,11].