HPGDS and diabetes mellitus: A reduction in oxidative stress markers, such as superoxide anion, hydroxyl radical, hydrogen peroxide, MDA, 8-isoprostane, 8-hydroxydeoxyguanine, nitro-tyrosine, and reduced/oxidized glutathione [30,31,32,33,34], as well as an improvement in the activities of antioxidant enzymes, such as superoxide dismutase, catalase, glutathione peroxidase, and glutathione-S-transferase, has been observed in the setting of diabetes [33,35,36].