In addition, FHL3 was overexpressed in PDAC tissue compared with its expression in adjacent non-tumor tissue in 49 paired paraffin-embedded sections of PDAC samples (p<0.001, Figure 1A and 1B), as same as the outcome of WB in eight matched fresh frozen PDAC samples (p<0.01, Figure 1D). Here, FHL3 is linked to neoplasm.