OGG1 and Chronic colitis: In addition, while Bacteroidetes Rikenellaceae AF12 taxa were also found to be present in WT gut microbiomes (but < 0.01% compared to Ogg1-/- gut microbiomes and > 5% in Ogg1-/- HFD), these microorganisms are of note as they have been reported to increase in the gut microbiomes of mouse models exhibiting DSS-induced or spontaneous chronic colitis in comparison to wild-type controls [87].