A high level of MUC1 expression (III/IV vs. I/II: OR = 2.17, 95% CI = 1.31–3.59, P = 0.002) was associated with advanced tumor stage in patients with CRC than MUC2 expression (III/IV vs. I/II: OR = 0.52, 95% CI = 0.36–0.76, P = 0.0008), but the association between MUC5AC expression and tumor stage was not significant. The gene discussed is MUC1; the disease is colorectal carcinoma.