SFTPD and acute kidney injury: The multivariate analysis showed that age (OR: 1.139, 95% CI 1.094–1.186; P = 0.000), SP-D rs721917CC genotype (OR: 1.996, 95% CI 1.078–3.697; P = 0.024), SOFA score (OR: 1.128, 95% CI 1.040–1.225; P = 0.004) were independent predictors of AKI (Table 6).