In medulloblastoma, we noticed the downregulation of subunits such as SMARCA2, ACTB, BCL7C, GLTSCR1/BICRA, SS18 and PBRM1 and upregulation of SMARCC1, SMARCD2, SMARCD3, BRD9, BCL7A, BCL7B, BCL11A and BCL11B in MYC silenced conditions (Fig. 5 and Supplementary Table 6). The gene discussed is SMARCC1; the disease is medulloblastoma.