TP53 and cancer: MirNet based network analysis of inter-miR interactions of 8 DEMs and with their targets suggested significant enrichment of various KEGG derived pathways (supplementary table 3) such as RNA transport (p < 0.001), pathways in cancer (p < 0.001), cell cycle (p < 0.001), mTOR signaling pathway (p < 0.001) and p53 signaling pathway (p < 0.001).