Powell et al. (2018) recently expanded these studies to a model of glioblastoma with Kras-transformed astrocytes. In Rac2D57N neutrophil-defective larvae, Kras+ cells are less proliferative. Additionally, cxcr1−/− larvae or larvae treated with a Cxcr1/2 inhibitor had decreased neutrophil recruitment to and proliferation of Kras+ cells, identifying a major signaling axis for neutrophil stimulation of transformed cell proliferation (Powell et al., 2018). Here, KRAS is linked to glioblastoma.