Though very few DEGs were apparent in GTx‐024‐treated tumor‐free controls (n = 27; Appendix Fig S13), GSEA focused on TF pathways revealed abundant coordinated signaling with regulation of β‐catenin (CTNNB1) target genes providing the most significant overlap (FDR < 1e‐5; Fig 8B). The gene discussed is CTNNB1; the disease is neoplasm.