GSK3B and Parkinson disease: It is well documented that GSK3β is a crucial pathogenic protein kinase for PD and makes a contribution in the regulation of neuronal apoptosis.12 Additionally, some studies carried out in vitro indicated the implication of GSK3β in MPP+‐mediated toxicity and mitochondrial dysfunction.27 Zhang et al12 observed enhanced expression of GSK3β at protein and mRNA levels in MPP+‐treated SH‐SY5Y cells in concentration‐ and time‐dependent manner.