Following intraperitoneal glucose and insulin challenge, serum glucose levels remained at higher levels in the HFD‐fed WT mice compared with the chow‐fed WT mice, the effect of which were augmented by CTRP9 deficiency, indicating the presence of glucose intolerance and insulin insensitivity (Figure 2D‐G). This evidence concerns the gene C1QTNF9 and glucose measurement.