More strikingly, LKB1 is recognized as a tumour suppressor gene, and inactivation of LKB1 predisposes people to various cancer.35 Meanwhile, a line of evidence suggests HFD‐induced obesity augments the risk of cancer as well as cardiovascular disease.36 Therefore, we speculate CTRP9 may have anticancer properties. This evidence concerns the gene C1QTNF9 and obesity due to melanocortin 4 receptor deficiency.