SIRT1 and posterior cortical atrophy: In contrast, other miRNAs may facilitate tumour cell proliferation by interacting with CDK inhibitors, such as p53 and ATM/ATR.32 SIRT1, which was shown to modulate both physiological and pathological processes in cells via acting on cell cycle proteins, including Rb, is now verified to be targeted by miR‐212 in some cancers.33, 34 miR‐212‐3p was shown by Ramalinga et al35 to prevent autophagy and angiogenesis while inducing cellular senescence by targeting SIRT1 in PCa.