MMP2 and coronary artery disorder: To assess the diagnostic accuracy of ADAMTS-5 in the detection of CAD, we performed ROC curve analysis and found that the area under the curve of ADAMTS-5 was 0.801, which was as high as that of MMP-2 (AUC = 0.748) and MMP-9 (AUC = 0.752) (Figure 5).