Cancer cells release large amounts of angiogenic molecules that induce the expression of angiogenic receptors in tumor blood vessels (e.g., endothelial growth factor (EGF) induces EGF receptors and vascular endothelial growth factor (VEGF) induces VEGF receptors (VEGFRs) in tumor-associated blood vessels) 29. The gene discussed is VEGFA; the disease is neoplasm.