To verify the correlation between VEGFR2 and TIPE, we examined VEGFR2 expression in the 55 CRC specimens by qRT-PCR, and the results showed that the relative VEGFR2 mRNA expression was also significantly higher in tumor tissues (n = 36) than in adjacent tissues (n = 19) (Figure 1e). The gene discussed is KDR; the disease is colorectal carcinoma.