A group of autoantibodies generally referred to as antiphospholipid antibodies (aPLs)—which include anticardiolipin (aCL) antibodies, anti-β2-glycoprotein I (β2-GPI) antibodies and lupus anticoagulant (LA) have been observed in autoimmune diseases including BD [17–20]. Here, ACLY is linked to Behcet disease.