According to the analysis of TCGA data, SOD2 expression was negatively associated with the levels of methylation at six CpG sites (cg06346099 and cg10698098 for BCa, cg09364756 and cg27624424 for PCa, cg18897905 and cg06346099 for RCC). The gene discussed is SOD2; the disease is posterior cortical atrophy.