LIPA and hereditary disease: Niemann Pick Disease (NPD) types A, B, and C; Infantile Neuronal Ceroid Lipofuscin (NCL or Batten's Disease); Gaucher's Disease; Lysosomal Acid Lipase (LAL) Deficiency; Familial Hypercholesterolemia (FH); Cerebrotendinous xanthomatosis (CTX); Smith-Lemli-Opitz Syndrome (SLOS); Sickle Cell Disease (SCD); and X-linked adrenoleukodystrophy (X-ALD) are all genetic diseases linked to cholesterol metabolism in some way.