These results indicate that PCAT7 upregulates TGFBR1 by disrupting the suppressive effect of miR‐324‐5p on TGFBR1 expression via competitively binding to miR‐324‐5p, which further activates TGF‐β signaling and promotes PCa bone metastasis. Here, TGFB1 is linked to posterior cortical atrophy.