Indeed, TGF‐β signaling has been widely reported to promote bone metastasis of multiple human cancers, including PCa and breast cancer (Dai et al., 2017; Fournier et al., 2015; Kang et al., 2005; Korpal et al., 2009; Yin et al., 1999). Here, TGFB1 is linked to breast carcinoma.