A total of 45 genes had been recorded as cancer genes in the Cancer Gene Census database, including BCL9L, SFPQ, PTPRT, UBR5, and PAX3 that were missed in a recent TCGA pancancer analysis33 that combines the genomic data for 33 cancer types with 26 existing bioinformatics tools, which highlights the validity and uniqueness of our method. Here, UBR5 is linked to cancer.