Reactome pathway analysis revealed an increased expression of genes related to the apoptosis/survival pathway, Toll-like receptor activation, and cytokine signaling, including Cγ chain receptor signaling pathways, in Trp1 Th-ctx cells in comparison to Trp1 Th tumor infiltrating lymphocytes (TILs) (Figure 1H). The gene discussed is TYRP1; the disease is neoplasm.