Another important set of genes increased in Post-CPB samples from both ToF and ASD patients coded for proinflammatory and chemotactic mediators (SOCS3, PTGS2, CCL2, CXCL2, RGS1, RGS2) and for molecules with metalloprotease (CYR61, ADAMTS1) and antioxidant activity (MT1M, MT2A). This evidence concerns the gene MT2A and atrial septal defect.