We previously described that WNT6 expression increases with glioma grade (Gonçalves et al., 2018), but it was still unknown whether this is associated with IDH mutation and/or 1p/19q codeletion status—the two most critical diagnostic molecular factors used in the new 2016 WHO classification of glioma (Louis et al., 2016). Here, WNT6 is linked to central nervous system cancer.