IL17RA and infection: To further clarify the role of IL-17 in this process, we fed IL-17 receptor-deficient C57BL/6 mice with either hypercaloric HBS or control AIN93G diet, and infected them with L. major. Interestingly, obese IL-17R-/- did not have augmented lesions, but presented high parasite load, and no difference in infection was observed between HBS fed or AIN93G fed mice.