OLFM4 and familial pancreatic carcinoma: We then analyzed the role of olfactomedin-4 (OLFM4), which was identified as a chemoresistance-related protein, in chemoresistance in an in vitro model and evaluated the expression and prognostic ability of OLFM4 by immunohistochemical (IHC) analysis in 80 pancreatic cancer tissues from human patients.