However, a newly identified mechanism of IFIT5 is regulation of the turnover of tumor suppressor microRNAs (miRNAs), including miR-363 and miR-128, resulting in increased expression of transcription factors of EMT such as slug and ZEB1, thereby enhancing invasion in renal cell carcinoma (RCC) (Lo et al., 2019). This evidence concerns the gene IFIT5 and renal cell carcinoma.