MOG and acute disseminated encephalomyelitis: In a recent study, Baumann et al. (95) compared the clinical and radiological findings of pediatric patients with ADEM and with and without anti-MOG antibodies; they highlighted that the group with anti-MOG had an MRI characterized by large, bilateral, and widespread lesions in the brain, with longitudinally extensive TM and a favorable outcome compared with children without anti-MOG.