The mRNA expression levels of Reg3A in tumor tissues from 36 Chinese patients with pancreatic cancer (23) were significantly higher in the patients with inflammation history than those without inflammation history, in tumors >3 cm than those ≤3 cm, in low differentiated tumors than high and middle differentiated tumors, and those in TNM stage III-IV than I-II. Here, REG3A is linked to familial pancreatic carcinoma.